According to an analysis by the federal Centers for Disease Control and Prevention published Tuesday (April 6) most children with a serious inflammatory illness linked to the coronavirus had initial COVID-19 infections with no symptoms or only mild ones, new U.S. research shows. (NIAID-RML via AP, File)

According to an analysis by the federal Centers for Disease Control and Prevention published Tuesday (April 6) most children with a serious inflammatory illness linked to the coronavirus had initial COVID-19 infections with no symptoms or only mild ones, new U.S. research shows. (NIAID-RML via AP, File)

Most kids with serious inflammatory illness had mild COVID-19

The post-infection condition tends to be milder in kids who were sicker with COVID-19, although more than half received intensive hospital care

Most children with a serious inflammatory illness linked to the coronavirus had initial COVID-19 infections with no symptoms or only mild ones, new U.S. research shows.

The unusual post-infection condition tends to be milder in kids who were sicker with COVID-19, although more than half of affected youngsters received intensive hospital care, according to an analysis by the federal Centers for Disease Control and Prevention published Tuesday in JAMA Pediatrics.

The study represents the largest analysis to date on U.S. cases of multisystem inflammatory syndrome in children and bolsters evidence that it is a delayed immune response to COVID-19. The study included almost 1,800 cases reported to the CDC from March 2020 through mid-January. Most were in kids younger than 15 but the study included up to age 20.

Upticks in cases have occurred two to five weeks after COVID-19 peaks and have followed spread of initial infections from urban to rural areas, the researchers said. More recent CDC data indicate there’s another emerging peak in the pediatric condition consistent with that trend.

State-reported cases through March 29 totalled 3,185 and included 36 deaths, the CDC’s website shows. State reports aren’t always timely so it is uncertain how many U.S. children developed the illness since the study ended.

Most kids who had COVID-19 don’t develop post-infection illness. Almost 3.5 million U.S. children and teens have tested positive for COVID-19, according to data compiled by the American Academy of Pediatrics and the Children’s Hospital Association.

The condition was first reported in Europe in late winter and spring of last year. Some cases, especially those that follow silent, undiagnosed COVID-19 infections, may be mistaken for Kawasaki disease, a rare condition that can cause red skin, swelling and heart problems.

Dr. Sean O’Leary, vice chairman of the pediatrics academy’s infectious diseases committee, said the inflammatory condition typically causes children to become very sick very quickly, but that most ‘’respond very well to treatment and the vast majority get completely better.’’

Treatments may include steroids and other medicines that can reduce inflammation.

The best way to prevent it is to prevent COVID-19 infections, ‘’which vaccines are very good at doing,’’ he said. COVID-19 vaccine studies in children are underway.

In the CDC analysis, fever was among the most common symptoms. Abdominal pain, vomiting, diarrhea and red skin rash occurred in at least half of affected kids. Almost one-third had heart inflammation or other cardiac involvement. These symptoms were least common among children up to age 4, who were also less likely to require intensive care than older children.

CoronavirusHealth

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Alberta chief medical officer of health Dr. Deena Hinshaw said on Thursday that the province has seen its first case of the B.1.617 variant. (Photography by Chris Schwarz/Government of Alberta)
Red Deer nears record number of active COVID-19 cases

Alberta reports 1,857 new cases of COVID-19, 1,326 new variants

Pastor Marco Ste-Marie of Rimbey United Church has spearheaded a new project called ‘Walking Through Rimbey’ to shine a light on various agencies and non-profit organizations. Photo submitted
‘Walking Through Rimbey’ continues to gather steam

Pastor Marco Ste Marie launched the project, aimed at building community connections, earlier this year

People line up outside an immunization clinic to get their Oxford-AstraZeneca COVID-19 vaccine in Edmonton, Tuesday, April 20, 2021. THE CANADIAN PRESS/Jason Franson
Alberta passes bill to give all workers paid leave to get COVID-19 vaccine shot

Labour Minister Jason Copping says Bill 71 will reduce barriers for Alberta workers to get vaccinated

Alberta completed 18,412 COVID-19 tests, as reported on Wednesday, for a test positivity rate of 9.5 per cent. (NIAID-RML via AP)
Highest daily count of 2021 so far: Alberta reports 1,699 COVID-19 cases

Variants now make up 59 per cent of Alberta’s active cases

Alberta’s chief medical officer of health Dr. Deena Hinshaw and Premier Jason Kenney say the province would look at adding additional COVID-19 measures in the coming weeks if the virus continues to spread. (Photo by Government of Alberta)
Walk-in COVID-19 vaccination clinic to open in Red Deer

Alberta adds 1,345 new cases of the virus

Canadian Prime Minister Justin Trudeau and United States President Joe Biden smile as they say farewell following a virtual joint statement in Ottawa, Tuesday, February 23, 2021. THE CANADIAN PRESS/Adrian Wyld
Trudeau pledges to cut emissions by 40% to 45% by 2030, short of U.S. goal

Trudeau announced target during a virtual climate summit convened by U.S. President Joe Biden

A health care worker prepares to test a Coastal GasLink field worker for COVID-19. (Coastal GasLink photo)
Alberta bill would protect health workers, care homes from some COVID-19 lawsuits

The bill proposes exempting a range of workers, including doctors, pharmacists and care-home operators, from being sued over COVID-19 unless it was for gross negligence

Journal de Montreal is seen in Montreal, on Thursday, April 22, 2021. The daily newspaper uses a file picture of Prime Minister Justin Trudeau dressed in traditional Indian clothing during his trip to India to illustrate a story on the Indian variant of the coronavirus. Paul Chiasson/The Canadian Press
Montreal newspaper blasted for front-page photo of Trudeau in India

Trudeau is wearing traditional Indian clothes and holding his hands together in prayer beside a caption that reads, ‘The Indian variant has arrived’

Education Minister Adriana LaGrange was in Red Deer on Friday to provide an update on the province's COVID-19 response in schools.
Photo by PAUL COWLEY/Advocate staff
Alberta government aiming to boost financial literacy among students

Government providing grants to organizations who will help design financial literacy programming

President Joe Biden holds a virtual bilateral meeting with Canadian Prime Minister Justin Trudeau. (AP Photo/Evan Vucci)
U.S. to help Canada with more COVID-19 vaccine supply, Biden says

The U.S. has already provided Canada with about 1.5 million doses of the AstraZeneca vaccine

In this image from video, former Minneapolis police Officer Derek Chauvin, center, is taken into custody as his attorney, Eric Nelson, left, looks on, after the verdicts were read at Chauvin’s trial for the 2020 death of George Floyd, Tuesday, April 20, 2021, at the Hennepin County Courthouse in Minneapolis, Minn. THE CANADIAN PRESS/Court TV via AP, Pool
George Floyd’s death was ‘wake-up call’ about systemic racism: Trudeau

Derek Chauvin was found guilty Tuesday on all three charges against him

sign
Alberta Biobord Corp. recently hosted a virtual open house from Stettler

The company plans to develop a fuel pellet and medium density fibre board (MDF) plant near the community

Most Read